Older Women Taking Statins Face Higher Risk of Diabetes

BRISBANE, Australia -- March 15, 2017 -- Older Australian women taking cholesterol-lowering statins face a significantly increased risk of developing diabetes, according to a study published in Drugs and Ageing.
Mark Jones, PhD, School of Public Health, University of Queensland, Herston, Queensland, Australia, said women over 75 faced a 33 percent higher chance of developing diabetes if they were taking statins.

The risk increased to over 50 percent for women taking higher doses of statins.

The research was based on prescription and survey data from 8372 women born between 1921 and 1926 who are regularly surveyed as part of the Women's Health Australia study (also known as the Australian Longitudinal Study on Women's Health).

"We found that almost 50 percent of women in their late 70s and 80s in the study took statins, and 5 percent were diagnosed with new-onset diabetes," Dr. Jones said.

"Statins are highly prescribed in this age group but there are very few clinical trials looking at their effects on older women," he said, adding, "The vast majority of research is on 40- to 70-year-old men."

"What's most concerning was that we found a 'dose effect' where the risk of diabetes increased as the dosage of statins increased," he said.

"Over the 10 years of the study most of the women progressed to higher doses of statins," Dr. Jones said.

"GPs and their elderly female patients should be aware of the risks," he noted, adding, "Those elderly women taking statins should be carefully and regularly monitored for increased blood glucose to ensure early detection and management of diabetes."

SOURCE: University of Queensland
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